@beerandjesus Investment teachers (Like Bogle, or Collins) taught us that for long term personal investment, the effective strategy is to invest in low cost broad market index funds and let the compound magic happen throughout the years.
Low cost broad market index funds are: S&P500, Total US stock market, or a global stock market.
The problem with Nasdaq based ETF is that it doesn't match the above description. It is not a broad market as it is only 100 companies and 50% of the total capital of those 100 are technology. So it is heavily tech focused and hence goes up and down with how well the tech sector goes. And that's where the volatility comes from.
Because of the high volatility, coupled with the high cost of the Nasdaq 100, you risk dragging down your portfolio compounding effect. I say "You risk" because there is a chance that Nasdaq will continue to outperform like it did in the past decade. But no one can guarantee that or not guarantee it won't go the other way badly. With the broad market funds, the risk is there, only a lot lesser.
It goes down to how much risk you are willing to do. You can play roulette with your portfolio and go all out on Nasdaq 100, or you can stay safe and do 100% VWCE, or even safer by 60% VWCE and 40% bonds. You have to research and learn about these risks so that you can take an informed decision with your investment portfolio.
I recommend you get yourself educated in personal investment. There is a book called "Simple Path to Wealth" by JL Collins. In my opinion, no one should start investing before they read this book. It has everything you need to know about investing. You just gotta watch out for the US specifics in the book that won't be applicable to you.